BACKGROUND: Combining targeted therapy has been extensively investigated in previously treated advanced non-small-cell lung cancer (NSCLC), but it is still unclear whether combining targeted therapy might offer any benefits against standard monotherapy with erlotinib.We thus performed a meta-analysis of randomized controlled trials to compare the e

The mammalian ovarian follicle is the complex reproductive unit comprising germ cell, somatic cells (Cumulus and Granulosa cells), and follicular fluid (FF): paracrine communication among the different cell types through FF ensures the development of a mature Kids Cardigan oocyte ready for fertilization.This paper is focused on non-coding RNAs in o

Chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) is an orphan receptor that regulates the expression of Appliance Cords genes involved in development and homeostasis.COUP-TFII is also dysregulated in cancer, where it plays important roles in oncogenesis and malignant progression.Recent studies have also investigated altered m

Plasmablastic lymphoma (PBL) is a rare form of lymphoma in people.PBL originates from plasmablasts and usually presents with swelling/mass in the mouth/neck.A 7-year-old Mongrel dog was presented for a large oral and neck mass.Cytology and histopathology were suggestive of a round Strontium Citrate cell tumor that was suspected to be lymphoma.An im